Two Wellington North teens were sent to a trauma centre early Sunday morning after a collision north of Arthur.
Wellington County OPP said a grey hatch-back left the roadway on Sideroad 10 East, east of Highway 6 at around 1:30 a.m.
Members of the Wellington North Fire Service and the Guelph Wellington Paramedic Service also responded.
The cause of the collision is still under investigation.
The roadway was closed as police investigate.
Anyone with information are asked to call 1-888-310-1122.