Two people were sent to hospital, one with significant injuries, following an early morning single-vehicle crash west of Seaforth.
Emergency crews responded to the collision at 2:28 a.m. on Sunday on Morrison Line between Mill Road and Roman Road in Huron East.
The crash kept the roadway closed for several hours while investigators were on scene. It was reopened shortly before noon.
Huron County OPP continue to investigate the cause of the collision with assistance of the OPP Traffic Incident Management Team.
Anyone with information is asked to contact police at 1-888-310-1122 or Crime Stoppers 1-800-222-8477.